Patients with hemoglobin H are more likely to develop gallstones and an enlarged spleen. Excessive iron can harm the spleen, heart, and liver. Iron may also accumulate from blood transfusions. If there is too much iron, the body will try to absorb more iron to compensate. Skeletal deformities may result as the body tries to produce more bone marrow. This is because neonates have a different type of hemoglobin, called fetal hemoglobin.Īfter 6 months “normal” hemoglobin starts replacing the fetal type, and symptoms may begin to appear. Symptoms will not show until the age of 6 months in most infants with beta thalassemia and some types of alpha thalassemia. The symptoms of thalassemia vary depending on the type of thalassemia. Share on Pinterest Jaundice can be a symptom of thalassemia.
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